Virtually full-length subtype F and F/D recombinant HIV-1 from Africa and South America

T Laukkanen, JK Carr, W Janssens, K Liitsola, D Gotte, FE McCutchan, E Op de Coul, M Cornelissen, L Heyndrickx, G van der Groen, MO Salminen

Research output: Contribution to journalA1: Web of Science-article

Abstract

For reliable classification of HIV-1 strains appropriate reference sequences are needed. The HIV-1 genetic subtype F has a wide geographic spread, causing significant epidemics in South America, Africa, and some regions of Europe. Previously only two full-length sequences of each of the HIV-1 subtype F subclusters F1 and F2 have been described. To extend the knowledge of subtype F variation on a complete genome level, three new virtually full-length F1 sequences were cloned and sequenced, two from Africa and one from South America. [abstract truncated]
Original languageEnglish
JournalVirology
Volume269
Pages (from-to)95-104
ISSN0042-6822
Publication statusPublished - 2000

Keywords

  • B780-tropical-medicine
  • Virology
  • HIV-1
  • Genetics
  • Genome
  • Classification
  • Phylogeny
  • Chimeric proteins
  • Molecular cloning
  • Molecular sequence data
  • Recombination
  • Sequence homology
  • Nucleic acids
  • Africa
  • America-Latin
  • Congo-Kinshasa
  • Africa-Central

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