Canine leishmaniasis in Algeria: true prevalence and diagnostic test characteristics in groups of dogs of different functional type

A Adel, C Saegerman, N Speybroeck, N Praet, B Victor, R De Deken, A Soukehal, D Berkvens

    Onderzoeksoutput: Bijdrage aan tijdschriftA1: Web of Science-artikel

    Uittreksel

    A Bayesian approach was used to assess the prevalence of Canine leishmaniasis and evaluate three serological diagnostic tests: indirect fluorescent antibody test (IFAT), direct agglutination test, and particle gel immuno-assay (PaGIA) for Canine leishmaniasis (CL) in Algiers. Four hundred and sixty-two dogs were involved in this study and divided in four groups according to their functional type: stray dogs, farm dogs, national guard dogs and pet dogs. The stray dog group showed the highest prevalence of leishmaniasis (11.7%), followed by the national guard dogs (9.7%) and the farm dogs (5.9%). IFAT was shown to be the most sensitive test in all groups. However, IFAT specificity was considerably lowered in the farm dog group: 65.2% versus 94.5% for the stray dogs. A considerable drop in PaGIA specificity was noted in the stray dogs group. The results of the current study demonstrate the variability of test characteristics in different situations and underline the danger of using standard values, without verifying their appropriateness for the specific purposes.
    TaalEngels
    TijdschriftVeterinary Parasitology
    Volume172
    Exemplaarnummer3-4
    Pagina's (van-tot)204-213
    Aantal pagina's10
    ISSN0304-4017
    DOI's
    StatusGepubliceerd - 2010

    Trefwoorden

    • B780-tropische-geneeskunde

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