Iron status of Burkinabe adolescent girls predicts malaria risk in the following rainy season

Loretta Brabin, Stephen A. Roberts, Halidou Tinto, Sabine Gies, Salou Diallo, Bernard Brabin

    Onderzoeksoutput: Bijdrage aan tijdschriftA1: Web of Science-artikel


    High levels of storage iron may increase malaria susceptibility. This risk has not been investigated in semi-immune adolescents. We investigated whether baseline iron status of non-pregnant adolescent girls living in a high malaria transmission area in Burkina Faso affected malaria risk during the following rainy season. For this prospective study, we analysed data from an interim safety survey, conducted six months into a randomised iron supplementation trial. We used logistic regression to model the risk of P. falciparum infection prevalence by microscopy, the pre-specified interim safety outcome, in relation to iron status, nutritional indicators and menarche assessed at recruitment. The interim survey was attended by 1223 (82%) of 1486 eligible participants, 1084 (89%) of whom were

    Artikel nummer1446
    Aantal pagina's15
    StatusGepubliceerd - 2020

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