Transmission of NS5A-inhibitor resistance-associated substitutions among men who have sex with men recently infected with hepatitis C virus genotype 1a

Stephanie Popping, Rosanne Verwijs, Lize Cuypers, Mark Claassen, Guido van den Berk, Anja De Weggheleire, Joop Arends, Anne Boerekamps, Richard Molenkamp, Marion Koopmans, Annelies Verbon, Charles Boucher, Bart Rijnders, David van de Vijver

Onderzoeksoutput: Bijdrage aan tijdschriftA1: Web of Science-artikel

Uittreksel

The transmission of direct-acting antiviral resistance-associated substitutions (RAS) could hamper hepatitis C virus (HCV) cure rates and elimination efforts. A phylogenetic analysis of 87 men who have sex with men recently infected with HCV genotype 1a placed one-third (28/87) in a large cluster, in which 96% harbored NS5A M28V RAS.

TaalEngels
TijdschriftClinical Infectious Diseases
Volume71
Exemplaarnummer8
Pagina's (van-tot)e215-e217
Aantal pagina's3
ISSN1058-4838
DOI's
StatusGepubliceerd - 2020

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